2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008

  • 2016

Araujo F, Goncalves J, Fonseca JE. 2016. Pharmacoeconomics of Biosimilars: What Is There to Gain from Them? Current Rheumatology Reports. doi: 10.1007/s11926-016-0601-0.

Araújo F, Gonçalves J, Fonseca JE. 2016. Biosimilar DMARDs: What Does the Future Hold? Drugs 76(6):629-37. doi: 10.1007/s40265-016-0556-5.

Araujo GR, Fujimura PT, Vaz ER, Silva TA, Rodovalho VR, Britto-Madurro AG, Madurro JM, Fonseca JE, Silva CH, Santos PS, Mourão AF, Canhão H, Goulart LR, Gonçalves J, Ueira-Vieira C. 2016. A novel reactive epitope-based antigen targeted by serum autoantibodies in oligoarticular and polyarticular juvenile idiopathic arthritis and development of an electrochemical biosensor. Immunobiology 221(5):634-40. doi: 10.1016/j.imbio.2016.01.006.

Azevedo-Pereira JM, Santos-Costa Q. 2016. HIV Interaction With Human Host: HIV-2 As a Model of a Less Virulent Infection. AIDS Rev 18(1):44-53.

Bártolo I, Calado R, Borrego P, Leitner T, Taveira N. 2016. Rare HIV-1 subtype J genomes and a new H/U/CRF02_AG recombinant genome suggests an ancient origin of HIV-1 in Angola. AIDS Research and Human Retroviruses 32(8):822-828.

Bettencourt P, Pires D and Anes E. 2016. Immunomodulating microRNAs of mycobacterial infections. Tuberculosis  97: 1-7.

Cunha-Santos C, Figueira TN, Oliveira SS, Borrego P, Rocha C, Couto A, Cantante C, Santos-Costa Q, Pereira J, Fontes CMGA, Taveira N, Aires-da-Silva F, Castanho MARB, Veiga AS, and Gonçalves J. 2016. Development of Synthetic Light-Chain Single-Domain Antibodies as Novel and Potent HIV Fusion Inhibitors. AIDS. 30 (11): 1691-1701.

Dörner T, Strand V, Cornes P, Gonçalves J, Gulácsi L, Kay J, Kvien TK, Smolen J, Tanaka Y, Burmester GR, 2016. The changing landscape of biosimilars in rheumatology. Ann Rheum Dis. pii: annrheumdis-2016-209166. doi: 10.1136/annrheumdis-2016-209166.

Duarte A, Jordão L, Subtil J. 2016. A importância dos biofilmes em otorrinolaringologia pediátrica. In: Luisa Monteiro, João Subtil (eds.) Otorrinolaringologia Pediátrica, Circulo Médico Edições, pp:373-375. Book Chapter.

Eusébio A, Araújo C, Madalena Andrade M, Duarte A. 2016. Escherichia coli in community urinary tract infections: commensal or pathogenic? Acta Urológica Portuguesa;33:37-42

Falcon-Neyra L, Palladino C, Navarro Gómez ML, Soler-Palacín P, González-Tomé MI, De Ory SJ, Frick MA, Fortuny C, Noguera-Julian A, Moreno EB, Santos JL,Olbrich P, López-Cortés LF, Briz V, Neth O; CoRISpe working group. 2016. Off-label use of rilpivirine in combination with emtricitabine and tenofovir in HIV-1-infected pediatric patients: A multicenter study. Medicine (Baltimore) 95(24):e3842.

Fernandes S, São-José C. 2016. More than a hole: the holin lethal function may be required to fully sensitize bacteria to the lytic action of canonical endolysins. Mol Microbiol. doi: 10.1111/mmi.13448.

Fernandes S, Labarde A, Baptista C, Jakutytè L, Tavares P, São-José C. 2016.  A non-invasive method for studying viral DNA delivery to bacteria reveals key requirements for phage SPP1 DNA entry in Bacillus subtilis cells. Virology 495:79-91. doi: 10.1016/j.virol.2016.05.004.

Figueiredo NLL, Canário J, O’Driscoll, Duarte A., 2016. Aerobic Mercury-resistant bacteria alter Mercury speciation and retention in the Tagus Estuary (Portugal). Ecotoxicol Environ Saf 124:60-67.

Gíria M, Santos L , Louro J, Rebelo-de-Andrade H. 2016. Reverse genetics vaccine seeds for influenza: Proof of concept in the source of PB1 as a determinant factor in virus growth and antigen yield. Virology 96:21 –27.

Godinho-Santos A, Hance A, Gonçalves J and Mammano F. 2016. CIB1 and CIB2 are HIV-1 helper factors involved in viral entry. Scientific Reports, Paper #SREP-16-01105A. Accepted for publication.

Goncalves J, Araujo F, Cutolo M, Fonseca JE. 2016. Biosimilar Monoclonal Antibodies: Preclinical and Clinical Development Aspects. Clinical and Experimental Rheumatology. Accepted.

Hurt A, Besselaar T, Daniels R, Ermetal B, Fry A, Gubareva L, Huang W, Lackenby A, Lee R, Lo J, Maurer-Stroh S, Nguyen H, Pereyaslov D, Rebelo-de-Andrade H, Siqueira M, Takashita E, Tashiro M, Tilmanis D, Wang D, Zhang W, Meijer A. 2016. Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2014–2015, Antiviral Research. 132:178-185.

Justino GC, Pinheiro PF, Roseiro APS, Knittel ASO, Gonçalves J, Justino MC and Carvalho MFNN. 2016. Camphor-based CCR5 blocker lead compounds – a computational and experimental approach. RSC Adv 6:56249-56259.

Kushkevycha I, Kollara P, Ferreira AL, Palmac D, Duarte A, Lopes MM,  Bartos M, Paukd K, Imramovskyd A, Jampileke J. 2016. Antimicrobial effect of salicylamide derivatives against intestinal sulfate-reducing bacteria. J Appl Biomedicine 2: 125–130.

Letra-Vilela R, Sánchez-Sánchez AM, Rocha AM, Martin V, Branco-Santos J, Puente-Moncada N, Santa-Marta M, Outeiro TF, Antolín I, Rodriguez C, Herrera F. 2016. Distinct roles of N-acetyl and 5-methoxy groups in the antiproliferative and neuroprotective effects of melatonin. Mol Cell Endocrinol 434:238-249. doi: 10.1016/j.mce.2016.07.012.

Machado D, Pires D, Perdigão J, Couto I, Portugal I, Martins M, Amaral L, Anes E, Viveiros M. 2016. Ion Channel Blockers as Antimicrobial Agents, Efflux Inhibitors, and Enhancers of Macrophage Killing Activity against Drug Resistant Mycobacterium tuberculosis. PLoS One. 11(2):e0149326. doi: 10.1371/journal.pone.0149326.

Perdigão P, Gaj T, Santa-Marta M, Barbas CF 3rd, Goncalves J. 2016. Reactivation of Latent HIV-1 Expression by Engineered TALE Transcription Factors. PLoS One. 11(3):e0150037. doi: 10.1371/journal.pone.0150037.

Pereira F, Madureira AM, Sancha S, Mulhovo S, Luo X, Duarte A, Ferreira MJ. 2016. Cleistochlamys kirkii chemical constituents: Antibacterial activity and synergistic effects against resistant Staphylococcus aureus strains. J. Ethnopharmacol. 178:180-187.

Phelan JE, Coll F, Bergval I, Anthony RM, Warren R, Sampson SL, Gey van Pittius NC, Glynn JR, Crampin AC, Alves A, Bessa TB, Campino S, Dheda K, Grandjean L, Hasan R, Hasan Z, Miranda A, Moore D, Panaiotov S, Perdigao J, Portugal I, Sheen P, de Oliveira Sousa E, Streicher EM, van Helden PD, Viveiros M, Hibberd ML, Pain A, McNerney R, Clark TG. 2016. Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages. BMC Genomics 17:151. doi: 10.1186/s12864-016-2467-y.

Piedade D, & Azevedo-Pereira, JM. 2016. MicroRNAs, HIV and HCV: a complex relation towards pathology. Reviews in Medical Virology, 26(3), 197–215. doi: 10.1002/rmv.1881.

Piedade D, & Azevedo-Pereira, JM. 2016. The Role of microRNAs in the Pathogenesis of Herpesvirus Infection. Viruses, 8(6), 156. doi:10.3390/v8060156.

Pineda-Peña A, Varanda J, Theys K, Bártolo I, Leitner T, Taveira N, Vandamme A and Abecasis AB. 2016. The hidden role of Angola on the early spread of the HIV-1 epidemic. Infection, Genetics  Evolution. In Press.

Pires D, Zagalo A, Santos C, Cota de Medeiros F, Duarte A, Lito L, Melo Cristino J, Caldeira L. 2016. Evolving epidemiology of carbapenemase-producing Enterobacteriaceae in Portugal: 2012 retrospective cohort at a tertiary hospital in Lisbon. J Hosp Infect 92(1):82-85.

Sardari S, Portugal I, ALKafri A, Moradi D, Ghavami G. 2016. Fragment-Based De Novo Design of Antimycobacterial Agents and In Vitro Potency Evaluation. Comb Chem High Throughput Screen. 19(3):238-45.

Vibe CB, Fenaroli F, Pires D, Wilson SR, · Bogoeva V, Kalluru R, Speth M, Anes E, Griffiths G and  Hildahl J. 2016. Thioridazine in PLGA nanoparticles reduces toxicity and improves rifampicin therapy against mycobacterial infection in zebrafish. Nanotoxicology 10(6):680-8. doi: 10.3109/17435390.2015.1107146.


Almeida CMM, Lopes MM. 2015. Fungi Isolated from Traditional and Exotic Apple Varieties from Portugal and Patulin Production. Journal of Pharmacy and Nutrition Sciences 5 (1):30-37. doi:10.6000/1927-5951.2015.05.01.5.

Araujo GR, Fonseca JE, Fujimura PT, Cunha-Junior JP, Silva CH, Mourão AF, Canhão H, Goulart LR, Gonçalves J, Ueira-Vieira C. 2015. Anti-type II collagen antibodies detection and avidity in patients with oligoarticular and polyarticular forms of juvenile idiopathic arthritis. Immunol Lett pii: S0165-2478(15)00041-3.

Araujo GR, Vaz ER, Fujimura PT, Fonseca JE, de Lima LM, Canhão H, Venturini G, Cardozo KH, Carvalho VM, Napimoga MH, Goulart LR, Gonçalves J, Ueira-Vieira C. 2015. Improved serological detection of rheumatoid arthritis: a highly antigenic mimotope of carbonic anhydrase III selected in a murine model by phage display. Arthritis Res Ther 17:168.

Azevedo Pereira JM. 2015. HIV-2 Interaction with Cell Receptors. J Human Virology and Retrovirology, 2(3), 1–3. doi: 10.15406/jhvrv.2015.02.00042.

Azevedo-Pereira, J. M., Canhão, P., Calado, A. M., Santos-Costa, Q., & Barroca, P. (2015). Inhibition of HIV Replication by Host Cellular Factors. In I. Bartholomew (Ed.), Trends in Basic and Therapeutic Options in HIV Infection – Towards a Functional Cure (pp. 75–104). InTech. doi:10.5772/60795.

Bandeira M, Carvalho PA, Duarte A and Jordao L. 2015. Bacterial biofilms, antibiotic resistance and healthcare-associated infections: a dangerous connection. Microscopy and microanalysis 21 (16): 38-39.

Baptista R, Madureira AM, Jorge R, Adão R, Duarte A, Duarte N, Lopes MM, Teixeira G. 2015. Antioxidant and Antimycotic Activities of Two Native Lavandula Species from Portugal. Evidence-Based Complementary and Alternative Medicine, 2015:1-10.

Briz V, Sepúlveda-Crespo D,  Diniz AR, Borrego P, Rodes B, de  la  Mata FJ,  Gómez R, Taveira N, and Muñoz-Fernández MÁ. 2015. Development  of  water-soluble  polyanionic carbosilane  dendrimers as novel and highly potent topical. Nanoscale. 7(35):14669-83. 10.1039/C5NR03644E.

Cabral V, Luo X, Junqueira E, Costa SS, Mulhoso S, Duarte A, Couto I, Viveiros M, Ferreira MJU 2015. Enhancing activity of antibiotics against Staphylococcus aureus: Zanthoxylum capense constituents and derivatives. Phytomedicine 4:469-476.

Coll F, McNerney R, Preston MD, Guerra-Assunção JA, Warry A, Hill-Cawthorne G, Mallard K, Nair M, Miranda A, Alves A, Perdigão J, Viveiros M, Portugal I, Hasan Z, Hasan R, Glynn JR, Martin N, Pain A, Clark TG. 2015. Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences. Genome Med 7(1):51. doi: 10.1186/s13073-015-0164-0.

Correia V, Santos L, Gíria M, Almeida-Santos M, Rebelo-de-Andrade H. (2015). Influenza A(H1N1)pdm09 Resistance and Cross-Decreased Susceptibility to Oseltamivir and Zanamivir Antiviral Drugs. Journal of Medical Virology 87:45-56.

Dalla Costa ER, Vasconcelos SE, Esteves LS, Gomes HM, Gomes LL, da Silva PA, Perdigão J, Portugal I, Viveiros M, McNerney R, Pain A, Clark TG, Rastogi N, Unis G, Rossetti ML, Suffys PN. 2015. Multidrug-Resistant Mycobacterium tuberculosis of the Latin American Mediterranean Lineage, Wrongly Identified as Mycobacterium pinnipedii (Spoligotype International Type 863 [SIT863]), Causing Active Tuberculosis in South Brazil. J Clin Microbiol. 53(12):3805-11.

Danilchanka O*, Pires D*, Anes E#, Niederweis M#. 2015. The Mycobacterium tuberculosis Outer Membrane Channel Protein CpnT Confers Susceptibility to Toxic Molecules. Antimicrob Agents Chemother 59(4):2328-36.*Joined first authors #corresponding authors.

Diniz AR, Canhões R e Taveira N. 2015. Profilaxia de pré-exposição da infecção por HIV. Revista Portuguesa de Farmacoterapia. 7: 91-109.

Figueiral MH, Fonseca P, Lopes MM, Pinto E, Pereira-Leite T, Sampaio-Maia B. 2015. Effect of Denture-Related Stomatitis Fluconazole Treatment on Oral Candida albicans Susceptibility Profile and Genotypic Variability. Open Dent J. 9: 46–51. doi: 10.2174/1874210601509010046.

Goddard N, Rebelo-de-Andrade H, Meijer A, Mc Couley J, Daniels R, Zambon M. (2015) Future Directions for the European Influenza Reference Laboratory Network in Influenza surveillance. Eurosurveillance, 30 July: 1-7.

Martínez-Bonet M, Palladino C, Briz V, Rudolph JM, Fackler OT, Relloso M,Muñoz-Fernandez MA, Madrid R. 2015. A Conserved GPG-Motif in the HIV-1 Nef Core IsRequired for Principal Nef-Activities. PLoS One. 10(12):e0145239.

Marto J, Baltazar D, Duarte A, Fernandes A, Gouveia L, Militão M, Salgado A, Simões S, Oliveira E, Ribeiro HM. 2015. Topical gels of etofenamate: in vitro and in vivo evaluation. Pharmaceutical Development and Technology  6:710-715.

Marto J, Gouveia L, Jorge IM, Duarte A, Gonçalves LM, Silva SMC, Antunes F, Pais AACC, Oliveira E, Almeida AJ, Ribeiro HM. 2015. Starch-based Pickering emulsions for topical drug delivery: a QbD approach. Colloids and Surfaces B Biointerfaces 135:183-92. doi:10.1016/j.colsurfb.2015.07.024.

Palladino C, Gómez ML, Soler-Palacín P, González-Tomé MI, De Ory SJ, Espiau M, Hoyos SP, León-Leal JA, Méndez M, Moreno-Pérez D, Guasch CF, Sierra AM, Guruceta IP, Guillén SM, Briz V; CoRISpe Working Group. 2015. Off-label use of maraviroc inHIV-1-infected paediatric patients in clinical practice. AIDS. 29(16):2155-9.

Pereira L, Diogo J, Mateus R, Pimentel M, Videira MA. 2015. Host-directed strategies using lipid nanoparticles to reduce mycobacteria survival. Journal of Nanoparticle Research 17(2). doi: 10.1007/s11051-015-2892-x).

Pires D, Valente E, Simões MF, Carmo N, Testa B, Constantino L and Anes E. 2015. Esters of Pyrazinoic Acid Are Active against Pyrazinamide-Resistant Strains of Mycobacterium tuberculosis and Other Naturally Resistant Mycobacteria In Vitro and Ex Vivo within Macrophages. Antimicrob. Agents Chemother. 59(12):7693-7699. doi: 10.1128/AAC.00936-15.

Proença D, Leandro C, Garcia M, Pimentel M, São-José C. 2015. EC300: a phage-based, bacteriolysin-like protein with enhanced antibacterial activity against Enterococcus faecalis. Appl Microbiol Biotechnol. 99:5137-49. doi: 10.1007/s00253-015-6483-7.

Rabna P, Ramos J, Ponce G, Sanca L, Mané M, Armada A, Machado D, Vieira F, Gomes VF, Martins E, Colombatti R, Riccardi F, Perdigão J, Sotero J, Portugal I, Couto I, Atouguia J, Rodrigues A, Viveiros M. 2015. Direct Detection by the Xpert MTB/RIF Assay and Characterization of Multi and Poly Drug-Resistant Tuberculosis in Guinea-Bissau, West Africa. PLoS One. 10(5):e0127536. doi: 10.1371/journal.pone.0127536.

Romão D, Sabino R, Veríssimo C, Viegas C, Barroso H, Duarte A, Solo-Gabriele H, Gunde-Cimerman N, Babič MN, Marom T, Brandão J. 2015. Children and Sand Play: Screening of Potential Harmful Microorganisms in Sandboxes, Parks, and Beaches. Current Fungal Infection Reports 3:155-163.

Santos LA, Solá S, Rodrigues CM, Rebelo-de-Andrade H. (2015) Distinct kinetics and pathways of apoptosis in influenza A and B virus infection. Virus Res 205:33-40.

Santos-Costa Q, Azevedo-Pereira, JM, Rocheta M. 2015. The HIV-2 SU Glycoprotein Influence Proviral Integration Dynamics into Human CD4+ T-Lymphocytes. HIV/AIDS Research and Treatment – Open Journal, 2(2): 55–64. doi:10.17140/HARTOJ-2-109.

Sousa S, Bandeira M, Carvalho PA, Duarte A, Jordão L. 2015. Nontuberculous mycobacteria pathogenesis and biofilm assembly. International Journal of Mycobacteriology 4: 36-43.

Takashita E, Meijer A, Lackenby A, Gubareva L, Rebelo-de-Andrade H, Besselaar T, Fry A, Gregory V, Leang SK, Huang W, Lo J, Pereyaslov D, Siqueira M, Wang D, Mak G, Zhang W, Daniels R, Hurt A, Tashiro M. (2015). Global update on the susceptibility of human influenza to neuraminidase inhibitors 2013-2014. Antiviral Research, 117:27-38.


2014  | voltar ao topo

Araújo F, Cordeiro I, Teixeira F, Gonçalves J, Fonseca JE. 2014. Pharmacology of biosimilar candidate drugs in rheumatology: a literature review. Acta Reumatol Port 39(1):19-26.

Barroca, P., Calado, M., & Azevedo-Pereira, J. M. (2014). HIV/dendritic cell interaction: consequences in the pathogenesis of HIV infection. AIDS Reviews 16(4), 223–235.

Bártolo I, Zakovic S, Martin F, Palladino C, Carvalho P, Camacho R, Thamm S, Clemente S, Taveira N. 2014. HIV-1 Diversity, Transmission Dynamics and Primary Drug Resistance in Angola. PLoS ONE. 9(12):e113626. doi: 10.1371/journal.pone.0113626.

Botelho A, Perdigão J, Canto A, Albuquerque T, Leal N, Macedo R, Portugal I, Cunha MV. 2014. Pre-multidrug-resistant Mycobacterium tuberculosis Beijing strain associated with disseminated tuberculosis in a pet dog. J Clin Microbiol. 52(1):354-6. doi: 10.1128/JCM.02800-13.

Brito PM and Antunes F. 2014. Estimation of kinetic parameters related to biochemical interactions between hydrogen peroxide and signal transduction proteins. Frontiers in Chemistry, section Cellular Biochemistry. Front Chem 2:82. doi: 10.3389/fchem.2014.00082.

C Casado; M Garcia-Arandia; C Pereira; M Catarino; V Parro; A Armentia; B Armentia; Pilar Barranco; S Quirce; M Blanca; PCampo; A Diaz-Perales. Component-resolved diagnosis of wheat flour allergy in baker’s asthma. Journal of Allergy and Clinical Immunology, April 2014, S0091-6749(14)00437-0

Coll F, McNerney R, Guerra-Assunção JA, Glynn JR, Perdigão J, Viveiros M, Portugal I, Pain A, Martin N, Clark TG. 2014. A robust SNP barcode for typing Mycobacterium tuberculosis complex strains. Nat Commun. 5:4812. doi: 10.1038/ncomms5812.

Coll F, Preston M, Guerra-Assunção JA, Hill-Cawthorn G, Harris D, Perdigão J, Viveiros M, Portugal I, Drobniewski F, Gagneux S, Glynn JR, Pain A, Parkhill J, McNerney R, Martin N, Clark TG. 2014. PolyTB: a genomic variation map for Mycobacterium tuberculosis. Tuberculosis (Edinb). 94(3):346-54. doi: 10.1016/

Figueiredo N, Canário J, Duarte A, Serralheiro ML, Carvalho C. 2014. Isolation and Characterization of Mercury-Resistant Bacteria from Sediments of Tagus Estuary (Portugal): Implications for Environmental and Human Health Risk Assessment. Journal of Toxicology and Environmental Health 77 (1-3):155-68.

Figueiredo NL, Areias A, Mendes R, Canário J, Duarte A, Carvalho C. 2014. Mercury-resistant Bacteria from Salt Marsh of Tagus Estuary: the influence of plants presence and mercury contamination levels. Journal of Toxicology and Environmental Health, A. 77(14-16):959-971.

Fonseca JE, Gonçalves J, Araújo F, Cordeiro I, Teixeira F, Canhão H, da Silva JA, Garcês S, Miranda LC, Ramiro S, Roxo A, Pimentel-Santos FM, Tavares V, Neto A, Sepriano A, Malcata A, Faustino A, Silva C, Ambrósio C, Duarte C, Miguel C, Barcelos F, Santos H, Cunha I, Ramos JC, Gomes JA, Pimentão JB, Costa L, Maurício L, Silva M, Bernardes M, Bogas M, Coelho PC, Monteiro P, Aguiar R, André R, Leitão R, Pimenta S, Meirinhos T, Fernandes S, Las V, Castelão W; Sociedade Portuguesa de Reumatologia. 2014. The Portuguese Society of Rheumatology position paper on the use of biosimilars. Acta Reumatol Port 39(1):60-71.

Giria M, Rebelo-de-Andrade H. (2014). Genetic evolution of PB1 in the zoonotic transmission of influenza A(H1N1) virus. Infection, Genetic and Evolution 27, 234-243.

Jorge R, Lopes MM,  Duarte A, Madureira A, Teixeira G. 2014. Portuguese Lavanders (Lavandula stoechas ssp. luisieri and Lavandula pedunculata) as a source of new antimycotics. Planta Medica 80(16) October. doi: 10.1055/s-0034-1394950.

Madureira AM, Duarte A, Correia AI, Teixeira G. 2014. Sanguisorba hybrida: pharmacognostic studies and antimicrobial activity evaluation of crude extracts. Revista de Ciências Agrárias 37, 4: 482-490.

Marto J, Baltazar D, Duarte A, Fernandes A, Gouveia L, Militão M, Salgado A, Simões S, Oliveira E, Ribeiro HM. 2014. Topical gels of etofenamate: in vitro and in vivo evaluation. Pharmaceutical Development and Technology  5:1-6.

Meijer A, Rebelo-de-Andrade H, Correia V, Besselaar T, Dayal RD, Fry A, Gregory V, Gubareva L, Kageyama T, Lackenby L, Lo J, Odagiri T, Pereyaslov D, Siqueira MM, Takashita E, Tashiro M, Wang D, Wong S, Zhang W, Daniels RS, Hurt AC. (2014). Global update on the susceptibility of human influenza viruses to neuraminidase inhibitors, 2012-2013. Antiviral Res. 110:31-41.

Mendes, J.J., Leandro, C., Mottola, C., Barbosa, R., Silva, F.A., Oliveira, M., Vilela, C:L:, Melo-Cristino, J., Górski, A., Pimentel, M., São-José, C., Cavaco-Silva, P., and Garcia, M. 2014. In vitro design of a novel lytic bacteriophage cocktail with therapeutic potential against organisms causing diabetic foot infections. J Med Microbiol. 63:1055-65. doi: 10.1099/jmm.0.071753-0.

Morais M, Cantante C, Gano L, Santos I, Lourenço S, Santos C, Fontes C, Aires da Silva F, Gonçalves J, Correia JD. 2014. Biodistribution of a 67Ga-labeled anti-TNF VHH single-domain antibody containing a bacterial albumin-binding domain (Zag). Nucl Med Biol pii: S0969-8051.

Palladino C,  Briz V, Bellón JM, Climent FJ,  de Ory SJ, Mellado MJ, Navarro ML, Ramos JT, Taveira N, de José MI, Muñoz-Fernández MÁ on the behalf of the working groups of Comunidad de Madrid and CoRISpES. 2014. Determinants of Highly Active Antiretroviral Therapy duration in HIV-1-infected paediatric patients in Madrid, Spain, from 1997 to 2012. PLoS ONE. 9(5): e96307. doi:10.1371/journal.pone.0096307.

Perdigão J, Macedo R, Machado D, Silva C, Jordão L, Couto I, Viveiros M, Portugal I. 2014. GidB mutation as a phylogenetic marker for Q1 cluster Mycobacterium tuberculosis isolates and intermediate-level streptomycin resistance determinant in Lisbon, Portugal. Clin Microbiol Infect. 20(5):O278-84. doi: 10.1111/1469-0691.12392.

Perdigão J, Silva H, Machado D, Macedo R, Maltez F, Silva C, Jordao L, Couto I, Mallard K, Coll F, Hill-Cawthorne GA, McNerney R, Pain A, Clark TG, Viveiros M, Portugal I. 2014. Unraveling Mycobacterium tuberculosis genomic diversity and evolution in Lisbon, Portugal, a highly drug resistant setting. BMC Genomics. 2014 Nov 18;15:991. doi: 10.1186/1471-2164-15-991.

Pereira Miguel J, Rebelo de Andrade H. Museu da Saúde. In: Maltez F, Ramalho de Almeida A. História das doenças infecciosas. 1ª Edição, ISBN: 978-989-98842, 2014, pag. 531-548.

Pimentel M. 2014.  Genetics of Phage Lysis. Microbiol Spectrum 2(1):MGM2-0017-2013. doi:10.1128/microbiolspec. MGM2-0017-2013.

Proença D, Velours C, Leandro C, Garcia M, Pimentel M, São-José C. 2014. A two-component, multimeric endolysin encoded by a single gene. Mol Microbiol. Nov 11. doi: 10.1111/mmi.12857.

Rijo P, Duarte A, Francisco AP, Semedo-Lemsaddek T, Simões MF. 2014. In vitro Antimicrobial Activity of Royleanone derivatives against Gram-Positive bacterial pathogens. Phytotherapy Research, 28 (1):76-81.

Sabino R, Rodrigues R, Costa I, Carneiro C, Cunha M, Duarte A, Faria N, Ferreira FC, Gargaté MJ, Júlio C, Martins ML, Nevers MB, Oleastro M, Solo-Gabriele H, Veríssimo C, Viegas C, Whitman RL, Brandão J. 2014. Routine screening of harmful microorganisms in beach sands: Implications to public health. Science of the Total Environment, 472: 1062–1069.

Santos-Costa Q, Lopes MM, Calado M, Azevedo-Pereira JM. 2014. HIV-2 interaction with cell coreceptors: amino acids within the V1/V2 region of viral envelope are determinant for CCR8, CCR5 and CXCR4 usage. Retrovirology 11:99. doi: 10.1186/s12977-014-0099-3.

Silva C, Perdigão J, Jordão L, Portugal I. 2014. Mycobacterial interspersed repetitive unit typing and mutational profile for multidrug-resistant and extensively drug-resistant tuberculosis surveillance in Portugal: a 3-year period overview. Int J Antimicrob Agents 44(6):546-51. doi:10.1016/j.ijantimicag.2014.06.021.

Taveira N. 2014. The HIV-2 envelope: structure, diversity and evolution. In: Encyclopedia of AIDS. Thomas J Hope, Mario Stevenson, Douglas Richman (Editors) Chapter 35, pp 1-6, Springer Reference. DOI 10.1007/978-1-4614-9610-6_35-1; Online ISBN 978-1-4614-9610-6.

Capítulos de livros

Azevedo-Pereira JM. 2014. Diagnóstico Laboratorial das Infecções Virais. In: H. Barroso, A. Meliço-Silvestre, & N. Taveira (Eds.), Microbiologia Médica (1st ed., Vol. 2, pp. 29–38). Lisboa. LIDEL.

Azevedo-Pereira JM. 2014. Mecanismos de Patogénese Viral. In H. Barroso, A. Meliço-Silvestre, & N. Taveira (Eds.), Microbiologia Médica (1st ed., Vol. 2, pp. 3–16). Lisboa: LIDEL.

Azevedo-Pereira JM, & Goncalves J. 2014. Princípios Gerais de Virologia: Estrutura e Replicação Viral. In H. Barroso, A. Meliço-Silvestre, & N. Taveira (Eds.), Microbiologia Médica (Vol.1, pp. 37–46). Lisboa: LIDEL.

Duarte A. 2014. Agentes antibacterianos: mecanismos de acção e resistência. In: H. Barroso, A.M. Silvestre, N. Taveira (eds.) Microbiologia Médica, Cap. 19, Lidel Edições Técnicas, Lisboa. pp 211-227.

Duarte A. 2014. Enterobacteriaceae. In: H. Barroso, A.M. Silvestre, N. Taveira (eds.) Microbiologia Médica, Cap. 27, Lidel Edições Técnicas, Lisboa. pp 342-357.

Gíria M, Rebelo de Andrade H, Valadas E. 2014. Doenças infecciosas emergentes. In: Barroso H, Melo Cristino J, Taveira N. Microbiologia Médica. Lidel – edições técnicas, 1.ª Edição, (ISBN:978-972-757-576-3). capítulo 51, pag.541-551.

Marinho A. e Taveira N. 2014. Fundamentos de Microbiologia. In: Microbiologia Médica, Vol. 1 Barroso H., Meliço Silvestre A. e Taveira N. (Eds), p. 3-36, LIDEL, Portugal.

Pimentel M. 2014. Genetics of Phage lysis, p 121–133. In G Hatfull and WR Jacobs, JR (eds), Molecular Genetics of Mycobacteria, 2nd ed. ASM Press, Washington, DC. doi:10.1128/9781555818845.

Rebelo de Andrade H. 2014. Orthomyxovirus. In: Barroso H, Melo Cristino J, Taveira N. Microbiologia Médica. Lidel – edições técnicas, 1.ª Edição, (ISBN:978-972-757-576-3) capítulo 45, pag.148-16.

Rebelo de Andrade H, Gíria M. 2014. Adenovírus. In: Barroso H, Melo Cristino J, Taveira N. Microbiologia Médica. Lidel – edições técnicas, 1º Edição, (ISBN:978-972-757-576-3), capítulo 79, pag. 58-67.

Saavedra MJ, Marinho A, Duarte A. 2014. Mycoplasma e Ureaplasma. In: H. Barroso, A.M. Silvestre, N. Taveira (eds.) Microbiologia Médica, Cap. 36, Lidel Edições Técnicas, Lisboa. pp 467-474.

Taveira N., Borrego P., e Gomes P. 2014. Antivirais. In: Microbiologia Médica, Barroso H., Meliço Silvestre A. e Taveira N. (Eds), p. 17-28, LIDEL, Portugal.

Taveira N., Rocha C., Pádua E. e Jani I. 2014. Retrovírus. In: Microbiologia Médica, Barroso H., Meliço Silvestre A. e Taveira N. (Eds), p. 221-240, LIDEL, Portugal.



Barroso H., Meliço Silvestre A. e Taveira N. (Coordenadores e editores). 2014. Microbiologia Médica, Vol. 1, LIDEL, Portugal. ISBN: 978-989-752-057-0

Barroso H., Meliço Silvestre A. e Taveira N. (Coordenadores e editores). 2014. Microbiologia Médica, Vol. 2, LIDEL, Portugal. ISBN: 978-972-757-576-3


Azevedo-Pereira J.M. (2013). HIV-2 Interaction with Target Cell Receptors, or Why HIV-2 is Less Pathogenic than HIV-1. In: Current Perspectives in HIV Infection, S.K. Saxena (Ed.), ISBN: 978-953-51-1057-6, InTech, 2013, pág: 411-45. DOI: 10.5772/53201. Available from:

Baptista, C., Barreto H.C. and São-José, C. (2103). High levels of DegU-P activate an Esat-6-Like secretion system in Bacillus subtilis. PLoS ONE. 8: e67840.

Bettencourt P, Marion S, Pires D, Santos FL, Lastrucci C, Carmo N, Blake J, Benes V, Griffiths G, Neyrolles O, Lugo-Villarino G and Anes E. 2013. Actin-binding protein regulation by microRNAs as a novel microbial strategy to modulate phagocytosis by host cells: the case of N-Wasp and miR-142-3p. Front. Cell. Infect. Microbiol. 3:19. doi: 10.3389/fcimb.2013.00019

Catalão, M.J., Gil, F., Moniz-Pereira, J., Pimentel, M. 2013 Diversity in bacteriophage lysis mechanisms. FEMS Microbiol. Rev. 37:554-571.doi: 10.1111/1574-6976.12006. [Epub ahead of print].

Gamboa PM, Gonzalez C, Pereira C, Catarino M, García-Lirio E, Soriano A, Pacios LF, Díaz-Perales A. Unlocking the resistence to wheat lipid transfer protein. Journal of Allergy and Clinical Immunology. 2013 Nov;132(5):1257-8.

Luo X.. , David P., Ainsa J.A., Gracia B., Duarte N ,Mulhovo S.,, Anes E.*, Ferreira M.J.U.* 2013 Zanthoxylum capense constituents with antimycobacterial activity against Mycobacterium tuberculosis in vitro, and ex vivo within human macrophages. accepted in Journal of Ethnopharmacology, 146(1):417-22, doi: 10.1016/j.jep.2013.01.013*Joined corresponding authors.

Machado D, Perdigão J, Ramos J, Couto I, Portugal I, Ritter C, Boettger EC, Viveiros M. High-level resistance to isoniazid and ethionamide in multidrug-resistant Mycobacterium tuberculosis of the Lisboa family is associated with inhA double mutations. J Antimicrob Chemother. 2013 Aug;68(8):1728-32.

Mahapatra S, Piechota C, Gil F, Ma Y, Huang H, Scherman M, Jones V, Martin Pavelka Jr. M, Moniz-Pereira J, Pimentel M, McNeil M, and Crick D. 2013. Mycobacteriophage Ms6 LysA is a peptidoglycan amidase and a useful analytical tool. Appl Environ Microbiol 79(3): 768-73.

Mariana Santa-Marta, Paula Brito, Ana Godinho-Santos, Joao Goncalves. Host factors and HIV-1 replication: clinical evidence and potential therapeutic approaches. Frontiers in Immunology. September 2013

Maurício Morais, Cátia Cantante, Lurdes Gano, Isabel Santos, Sara Lourenço, Catarina Santos, Carlos Fontes, Frederico Silva, João Gonçalves, João D. G. Correia. Biodistribution of a 67Ga-labeled anti-TNF VHH single domain antibody containing a bacterial albumin-binding domain (Zag). Nuclear Medicine Biotechnology. October 2013

Mestre O, Hurtado-Ortiz R, Dos Vultos T, Namouchi A, Cimino M, Pimentel M, Neyrolles O, Gicquel B. 2013. High Throughput Phenotypic Selection of Mycobacterium tuberculosis Mutants with Impaired Resistance to Reactive Oxygen Species Identifies Genes Important for Intracellular Growth. PLoS ONE 8(1): e53486. doi:10.1371/journal.pone.0053486

Perdigão J, Macedo R, Silva C, Machado D, Couto I, Viveiros M, Jordao L, Portugal I. From multidrug-resistant to extensively drug-resistant tuberculosis in Lisbon, Portugal: the stepwise mode of resistance acquisition. J Antimicrob Chemother. 2013 Jan;68(1):27-33.

Perdigão J, Macedo R, Machado D, Silva C, Jordão L, Couto I, Viveiros M, Portugal I. GidB mutation as a phylogenetic marker for Q1 cluster Mycobacterium tuberculosis isolates and intermediate-level streptomycin resistance determinant in Lisbon, Portugal. 2013 (aceite no Clin Microb Inf).

Pinto, D., São-José, C., Santos, M.A. and Chambel, L. (2013). Characterization of two resuscitation promoting factors of Listeria monocytogenes. Microbiology. 159: 1390-1401.

Pozo F, Lina B, Rebelo-de-Andrade H, Enouf V, Kossyvakis A, Broberg E, Daniels R, Lackenby A, Meijer A. Guidance for Clinical and public health laboratories testing for influenza virus antiviral drug susceptibility in Europe.J Clin Virol. 2013, 57:5-12

Rijo P, Duarte A, Francisco AP, Semedo-Lemsaddek T, Simões MF. In vitro Antimicrobial Activity of Royleanone Derivatives Against Gram-Positive Bacterial Pathogens. Phytotherapy Research. 2013 Mar 11. doi: 10.1002/ptr.4961

Silva C, Perdigao J, Alverca E, de Matos AP, Carvalho PA, Portugal I, Jordao L. Exploring the contribution of mycobacteria characteristics in their interaction with human macrophages. Microsc Microanal. 2013 Oct;19(5):1159-69.

Catalão, M.J., Gil, F., Moniz-Pereira, J., São-José, C. and Pimentel, M. (2012). Diversity in bacterial lysis systems: bacteriophages show the way. FEMS Microbiol. Rev. 37: 554-571

da Silva, F. A., Li, M., Rato, S., Maia, S., Malhó, R., Warren, K., Harrich, D., Craigie, R., Barbas, C. and Goncalves, J. (2012), Recombinant rabbit single-chain antibodies bind to the catalytic and C-terminal domains of HIV-1 integrase protein and strongly inhibit HIV-1 replication. Biotechnology and Applied Biochemistry, 59: 353–366. doi: 10.1002/bab.1034

Espírito-Santo M., Santos-Costa Q, Calado M., Dorr P., Azevedo-Pereira J. M.* Susceptibility of HIV-2 primary isolates to CCR5 and CXCR4 monoclonal antibodies, ligands and small molecule inhibitors. AIDS Research and Human Retroviruses, (2012), Vol. 28: 478–485. (Online Ahead of Print: October 3, 2011; doi: 10.1089/aid.2011.0124).

Fernandes S, Proença D, Cantante C, Silva FA, Leandro C, Lourenço S, Milheiriço C, de Lencastre H, Cavaco-Silva P, Pimentel M, São-José C. 2012. Novel Chimerical Endolysins with Broad Antimicrobial Activity Against Methicillin Resistant Staphylococcus aureus. Microb Drug Resist. 18: 333-343. doi: 10.1089/mdr.2012.0025.

Gíria MT, Rebelo de Andrade H, Santos LA, Correia VM, Pedro SV, Santos MA. Genomic signatures and antiviral drug susceptibility profile of A(H1N1)pdm09. J Clin Virol.2012,Feb;53(2):140-4.

Jakutytė, L., Lurz, R., Baptista, C., Carballido-Lopez, R., São-José, C., Tavares, P. and Daugelavicius, R. (2012). First steps of bacteriophage SPP1 entry into Bacillus subtilis. Virology. 422: 425-434

Janeiro E, Guimarães J, Stenman UH, Catarino M, Itkonen O. Validation aand comparation of tumor associated trypsin inhibitor (TATI) immunoassaysClin Chim Acta. 2012 Aug 16;413(15-16):1244-8.

Macedo R., A.F. Antunes, M. Villar, I. Portugal. Multidrug and extensively drug-resistant tuberculosis in Lisbon and Vale do Tejo, Portugal, from 2008 to 2010. Int J Mycobac. 2012; I: 131-136.

Machado D, Couto I, Perdigão J, Rodrigues L, Portugal I, Baptista P, Veigas B, Amaral L, Viveiros M. Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis. PLoS One. 2012;7(4):e34538.

Oliveira, S. S., Aires da Silva, F., Lourenco, S., Freitas-Vieira, A., Cunha Santos, A. C. and Goncalves, J. (2012), Assessing combinatorial strategies to multimerize libraries of single-domain antibodies. Biotechnology and Applied Biochemistry, 59: 193–204. doi: 10.1002/bab.1011

Pimenta J, Domingos A, Santos P, Marques CC, Cantante C, Santos A, Barbas J, Baptista M, Horta A, Viegas A, Mesquita P, Goçalves J, Fontes C, Prates J, Pereira R. (2012) Is prnt a Pseudogene? Identification of Ram Prt in Testis and Ejaculated Spermatozoa. PLoS ONE 7(8): e42957. doi:10.1371/journal.pone.0042957

Proença D, Fernandes S, Leandro C, Silva FA, Santos S, Lopes F, Mato R, Cavaco-Silva P, Pimentel M, São-José C. 2012. Phage Endolysins with Broad Antimicrobial Activity Against Enterococcus faecalis Clinical Strains. Microb Drug Resist. 18: 322-332. doi: 10.1089/mdr.2012.0024.

Rodrigues JF, Casado A, Palos C, Santos C, Duarte A, Fernandez-Llimos F. A computer-assisted prescription system to improve antibacterial surgical prophylaxis. Infection Control and Hospital Epidemiology, 2012; 33 (4): 435-437

Sacadura-Leite E, Sousa-Uva A, Rebelo-de-Andrade H. Antibody response to the influenza vaccine in healthcare workers. Vaccine. 2012 Jan 5;30(2):436-41.

Vinga, I., Baptista, C., Auzat, I., Petipas, I., Lurz, R., Tavares, P., Santos, M.A. and São-José, C. (2012). Role of bacteriophage SPP1 tail spike protein gp21 on host cell receptor binding and trigger of phage DNA ejection. Mol. Microbiol. 83: 289-303


Brachkova MI, Marques P, Rocha J, Sepodes B, Duarte MA, Pinto JF. Alginate films containing Lactobacillus plantarum as wound dressing for prevention of burn infection. Journal of Hospital Infection. 2011,79: 375-377

Cadima-Couto I, Saraiva N, Santos AC, Goncalves J. HIV-1 Vif Interaction with APOBEC3 Deaminases and its Characterization by a New Sensitive Assay. J Neuroimmune Pharmacol. 2011 Jan 29.

Catalão, M.J., Gil, F., Moniz-Pereira, J., Pimentel, M. 2011. The endolysin-binding domain encompasses the N-terminal region of the mycobacteriophage Ms6 gp1 chaperone. J Bacteriol. 193: 5002-5006. doi: 10.1128/JB.00380-11.

Catalão, M.J., Gil, F., Moniz-Pereira, J., and Pimentel, M. 2011. Functional analysis of the holin-like proteins of mycobacteriophage Ms6. J Bacteriol 193: 2793-2803. doi: 10.1128/JB.01519-10.

Catalão, M.J., Milho, C., Gil, F., Moniz-Pereira J., Pimentel, M. 2011. A second endolysin gene is fully embedded in-frame with the lysA gene of mycobacteriophage Ms6. PLoS One. 6:e20515. doi: 10.1371/journal.pone.0020515.

Corte-Real S, Aires da Silva F, Goncalves J. Development of antibody fragments for therapeutic applications. Peptide Drug Discovery and Development. Translational Research in Academia and Industry. Willey 2011.

Esteves AI, Nicolai M, Humanes M, Goncalves J. Sulfated Polysaccharides in Marine Sponges: Extraction Methods and Anti-HIV Activity. Mar Drugs. 2011 Jan 24;9(1):139-53.

Gomes C., Azevedo-Pereira J.M.* Performance of the VIKIA® HIV1/2 rapid test – evaluation of the reliability and sensitivity of early positive results. Journal of Virological Methods 2011, Vol. 173: 353-356.

Gonçalves, J. Inovação em Portugal: Problemas e Desafios. Aspectos. Câmara de Comércio e Indústria Luso-Francesa. Julho 2011 (nº 152).

Jakutyte, L., Baptista, C., São-José, C. Daugelavicius, R., Carballido-López, R. and Tavares, P. (2011). Bacteriophage infection in rod-shaped Gram-positive bacteria: evidence for a preferential polar route for phage SPP1 entry in Bacillus subtilis. J. Bacteriol. 193: 4893-4903.

Lopes, MM. “Infecções fúngicas em meio hospitalar e terapêutica” (Livro) – Lisboa: [s.n.], 2011 – Edição MJGS, Lda. Edição exclusiva para a Merck Sharp & Dohme, Lda. ISBN 978-989-970-005-5

Marques, J; , Gonçalves J.; Simões, P.; Mata, A.; Deng, H.; Li, Y.; ,Corby, P.M:, Phelan, J. Immunity, Microorganisms and HIV in the Oral Cavity: Pilot Study. J Dent Res Spec Issue 90(A) 870, 2011

Marques, J; Marques, D.; Oliveira, M.; Veiga, M.; Simões, P.; Gonçalves, J.; Malamud, D.; Mata, A. HIV-1 Impact On Oral Health Related Quality Of Life. J Dent Res Spec Issue 90(A) 678, 2011

Narciso A, Nunes F, Amores T, Lito L, Melo-Cristino J, Duarte A. Persistence of uropathogenic Escherichia coli strains in the host for long periods of time: relationship between phylogenetic groups and virulence factors. European Journal of Clinical Microbiology and Infectious Diseases, 2011; 31 (6):1211-1217

Nunes B, Viboud C, Machado A, Ringholz C, Rebelo-de-Andrade H, Nogueira P, Miller M. Excess mortality associated with influenza epidemics in Portugal, 1980 to 2004.PLoSOne.2011;6(6):e20661.

Perdigão J, Macedo R, Silva C, Pinto C, Furtado C, Brum L, Portugal I. Tuberculosis Drug-Resistance in Lisbon, Portugal: a Six-Year Overview. Clinical Microbiology and Infection 2011. 17(9):1397-402.

Santos, LA, Correia V, Giria M, Pedro S, Santos MM, Silvestre MJ, Rebelo-de-Andrade H. Genetic and Antiviral Drug Susceptibility Profiles of Pandemic A(H1N1)v Influenza Virus Circulating in Portugal. Influenza and Other Respiratory Viruses. 2011; 5 (Suppl. 1), 294–300.

Calado M., Matoso P., Santos-Costa Q., Espirito-Santo M., Machado J., Rosado L., Antunes F., Mansinho K., Lopes M. M., Maltez F., Santos-Ferreira M. O., Azevedo-Pereira J. M.* Coreceptor usage by HIV-1 and HIV-2 primary isolates: The relevance of CCR8 chemokine receptor as an alternative coreceptor. Virology 2010, Vol. 408: 174-182.

Catalão, M.J., Gil, F., Moniz-Pereira, J., and Pimentel, M. 2010. Mycobacteriophage Ms6 encodes a chaperone–like protein involved in the endolysin delivery to the peptidoglycan. Mol Microbiology 77: 672-686.

Correia V, Rebelo-de-Andrade H, Santos L, Lackanby A, Zambon M. Antiviral drug profile of seasonal influenza viruses circulating in Portugal from 2004/2005 to 2008/2009 winter season. Antiviral Research 2010, 86, 128-136.

Corte-Real S, Fonseca, L. , Barbas CF 3rd, Goncalves J. Intrabody-based mapping of Latency-Associated Nuclear Antigen from Kaposi’s Sarcoma-Associated Herpesvirus show conserved epitopes for viral latency inhibition. Virology: Research and Treatment 2010:2 1-16

Da Silva GJ, Mendonça N, Batista G, Duarte A. Sequence types of Portuguese carbapenem-resistant Acinetobacter baumannii isolates collected over 10 years. Journal of Antimicrobial and Chemotherapy 2010; 65: 2254-2256.

Gil, F., Grzegorzewicz, A.E. Catalão, M.J., Vital, J., McNeil, M., and Pimentel, M. 2010. Mycobacteriophage Ms6 LysB, specifically targets the outer membrane of Mycobacterium smegmatis. Microbiology 156: 1497-1504

Iris Cadima-Couto and Joao Goncalves. Towards Inhibition of Vif-APOBEC3G Interaction: Which Protein to Target? Advances in Virology. Volume 2010 (2010), Article ID 649315. doi:10.1155/2010/649315

Mishra BB, Moura- Alves P, Sonawane A, Hacohen N, Griffiths G, Moita LF and Anes E. .2010. Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome. Cell Microbiol. 12(8):1046-63.

Perdigão J, Macedo R, Malaquias A, Ferreira A, Brum L, Portugal I. Genetic Analysis of Extensive Drug-Resistant Mycobacterium tuberculosis in Lisbon, Portugal. Journal of Antimicrobial Chemotherapy 2010. 65(2):224-7.

Rato S, Maia S, Brito PM, Resende L, Pereira CF, et al. 2010. Novel HIV-1 Knockdown Targets Identified by an Enriched Kinases/Phosphatases shRNA Library Using a Long-Term Iterative Screen in Jurkat T-Cells. PLoS ONE 5(2): e9276. doi:10.1371/journal.pone.0009276.

Rebelo-de-Andrade H, Pereira C, Gíria M, Prudencio E, Brito MJ, Calé E, Taveira N. Outbreak of acute respiratory infection among infants in Lisbon, Portugal, caused by human adenovirus serotype 3 and a new 7/3 recombinant strain. Journal of Clinical Microbiology 2010 April; 48(4):1391-6.

Silvério A., MM Lopes, G Freitas. Determination of fungal contamination, aflatoxin B1 and ochratoxin A content in peanuts available in portuguese market. Journal of Biotechnology. 2010; 150S: S1-S576.

Veigas B, Machado D, Perdigão J, Portugal I, Couto I, Viveiros M, Baptista P. AU-nanoprobes for detection of SNPs associated with antibiotic resistance in Mycobacterium tuberculosis. Nanotechnology 2010. 21(41):415101.

Viveiros M, Martins M, Couto I, Rodrigues L, Machado D, Portugal I, Amaral L. Molecular tools for rapid identification and novel effective therapy against MDRTB/XDRTB infections. Expert Review of Anti-infective Therapy. 2010. 8(4):465-80. Review.


Cadima-Couto I, Freitas-Vieira A, Nowarski R, Britan-Rosich E, Kotler M, Goncalves J. Ubiquitin-fusion as a strategy to modulate protein half-life: A3G antiviral activity revisited. Virology. 2009 Oct 25;393(2):286-94. Epub 2009 Aug 29.

Gonçalves A, Pedro S, Duarte A, Nunes ML. Effect of enriched oxygen atmosphere storage on the quality of live clams (Ruditapes decussatus). International Journal of Food Science and Technology. 2009, 44: 2598-2605

Jiang X, Lu C, Gao F, Wang F, Zhang W, Portugal I, Xu P, Wang H, Zhang Y. A rapid and simple method for identifying Mycobacterium tuberculosis W-Beijing strains based on detection of a unique mutation in Rv0927c by PCR-SSCP. Microbes and Infection 2009. (3):419-23.

Kuehnel M, Rybin V, Anand P, Anes E and Gareth Griffiths. 2009. Lipids regulate P2X7 receptor-dependent actin assembly by phagosomes via ADP translocation and ATP synthesis in the phagosome lumen. J Cell Science 122(Pt 4):499-504

Lidia Fonseca1, Frederico Aires-da-Silva, Mariana Santa-Marta, Joao Barata, Carlos Barbas III, Joao Goncalves. Programming specificity of lentiviral cell targeting using anti-FITC single-chain antibody. Human Gene Therapy. 20:1417–1545 (November 2009).

Marinho C, Neres R, Epiphanio S, Gonçalves LA, Neres R, Marinho C, Gonçalves LA, Catarino MB, Penha- Gonçalves C. Recrudescent plasmodium berghei from pregnant mice display enhanced binding to the placenta and induces protection in multigravida. PLoS One. 2009 May 20;4(5):e5630.

Perdigão J, Macedo R, Ribeiro A, Brum L, Portugal I. Genetic characterization of the ethambutol resistance determinating region in Mycobacterium tuberculosis: prevalence and significance of embB306 mutations. International Journal of Antimicrobial Agents 2009. 33(4):334-8.

Perdigão J, Milho C, Carrilho L, Brum L, Portugal I. Genotypic analysis of Mycobacterium tuberculosis isolates from a Lisbon hospital in Portugal. Revista Portuguesa de Pneumologia 2009. Vol XV(5):761- 769

Santos-Costa, Q., K. Mansinho, J. Moniz-Pereira, and J. M. Azevedo-Pereira*. Characterization of HIV-2 chimeric viruses unable to use CCR5 and CXCR4 coreceptors. Virus Research 2009, Vol. 142: 41-50.

Santos-Costa Q, R. Parreira, J. Moniz-Pereira, J. M. Azevedo-Pereira*. Molecular characterization of the env gene of two CCR5/CXCR4-independent human immunodeficiency 2 primary isolates. Journal of Medical Virology 2009, Vol. 81: 1869-81.

Simões MF, Valente E, Rodriguez-Gomez MJ, Anes E* and Constantino L*. 2009. Lipophilic POA amide and ester prodrugs. Stability, activation and activity against M.tuberculosis. Eur. J. Pharm. Sci, 37:257-263. * joined corresponding authors


Frederico Aires da Silva, Sofia Corte-Real and Joao Goncalves. Recombinant antibodies as therapeutic agents: pathways for modeling new biodrugs. BioDrugs. 2008;22(5):301-14.

Gil, F., Catalão, M.J., Moniz-Pereira, J., McNeil, M., Leandro, P., and Pimentel, M. 2008. The lysis cassette of mycobacteriophage Ms6 encodes an enzyme with lypolitic activity. Microbiology 154: 1364-1371.

Gutierrez, MG*, Mishra, BB*, Jordao, ML, Elliot, E, Anes, E and Griffiths, G. 2008. NF-kappa B activation controls phago-lysosome fusion-mediated killing of mycobacteria by macrophages. J. Immunology 18(4): 2651-63 *joined first authors

Jordao, L., Bleck, CKE., Mayorga, L., Griffiths, G, and Anes, E. 2008. On the killing of mycobacteria by macrophages. Cell Microbiol 10(2): 529-48.

Jordao L, Lengeling A, Bordat Y, Boudou F, Gicquel G, Neyrolles O, Becker PD, Guzman C, Griffiths G and Anes E. 2008. Effects of omega-3 and -6 fatty acids on Mycobacterium tuberculosis in macrophages and in mice. Microb Infect 10 (12-13):1379-86.

Lopes, MM, R Ribeiro, D Carvalho, G Freitas. In vitro antimicrobial susceptibility of Prototheca spp. isolated from bovine mastitis in a Portugal dairy herd. Journal de Mycologie Médicale. 2008; 18: 205-209.

Neres R, Marinho C, Gonçalves LA, Catarino MB, Penha- Gonçalves C. Malaria recrudescence in mice pregnancy. The American Journal of the Tropical Medicine and Hygiene, 2008,79(6):625 (Supplement)

Neres R,  Marinho C, Gonçalves LA, Catarino MB, Penha- Gonçalves C. Pregnancy outcome and placenta pathology in Plasmodium berghei ANKA infected mice reproduce the pathogenesis of severe Malaria in pregnant Women. PloS ONE,2008,3(2):1608

Perdigão J, Macedo R, João I, Fernandes E, Brum L, Portugal I. Multidrug-Resistant Tuberculosis in Lisbon, Portugal: A Molecular Epidemiological Perspective. Microbial Drug Resistance 2008. 14(2):133-43.

Portugal I, Barreiro L, Vultos T, Macedo R, Furtado C, Fonseca-Antunes A, Brum L. Molecular epidemiology of Mycobacterium tuberculosis in Lisbon. Revista Portuguesa de Pneumologia 2008. Vol XIV(2):239- 259.

Rolim I, Boavida JM, Duarte R, Pina R, Valadas C, Pratas S, Carvalho R, Vieira R, Ligeiro D, Sancho M, Catarino MB, Penha-Gonçalves C. Susceptibilidade genética à Diabetes Tipo 1 na população Portuguesa. Revista Portuguesa de Diabetes, 2008 (1) Suppl:25-28

Sofia Corte-Real, Lídia Fonseca and Joao Goncalves. KSHV Latency in Transformed B-cells: The Role of LANA1 as a Therapeutic Target. Virology: Research and Treatment 2008:1 43–48